Shortened apheresis-based extra-corporeal photochemotherapy for acute refractory GVHD in children: a prospective study
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چکیده
منابع مشابه
CHEST PAIN IN CHILDREN A PROSPECTIVE STUDY
Thirty five children with a primary complaint of chest pain were prospectively studied. The average age was 9.7 years for boys and 8. 9 years for girls 60% were male. The most frequently diagnosed cause was psychogenic (54.2%). Forty percent of the patients were classified as having idiopathic chest pain. Precordial pain was encountered in 2. 9%), along with costochondritis and mitral val...
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IT is to extra-corporeal circulation that cardiac surgery owes its present momentum. Without this system of circulating blood outside the body through a variety of pumps and oxygenating devices, it is fair to say that no adequate access to the interior of the heart could have been obtained. Correction of congenital defects within the heart demands that the interior of its cavities be available ...
متن کاملHow I treat refractory acute GVHD.
Graft-versus-host disease (GVHD) after allogeneic hematopoietic cell transplantation (HCT) is associated with considerable morbidity and mortality, particularly in patients who do not respond to primary therapy, which usually consists of glucocorticoids (steroids). Approaches to therapy of acute GVHD refractory to "standard" doses of steroids have ranged from increasing the dose of steroids to ...
متن کاملSteroid-Refractory Acute GVHD: Predictors and Outcomes
Patients with steroid-resistant acute graft versus host disease (aGVHD) have a dismal prognosis, with mortality rates in excess of 90%. We sought to identify a subgroup of patients less likely to benefit from initial therapy with corticosteroids as well as the impact of response on day 14 on outcome. Retrospective evaluation was performed of patients with biopsy-proven aGVHD treated with cortic...
متن کاملExtracorporeal photochemotherapy for the treatment of steroid-resistant chronic GVHD.
Chronic graft-versus-host disease (GVHD) is a major limitation of successful allogeneic hematopoietic stem cell transplantation (HSCT). Extracorporeal photochemotherapy (ECP) has been tested extensively in small cohorts of patients with chronic GVHD. In this study, we retrospectively evaluated 71 patients with severe chronic GVHD treated with ECP. Response rate was 61% (n = 43), and 14 patients...
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ژورنال
عنوان ژورنال: Bone Marrow Transplantation
سال: 2016
ISSN: 0268-3369,1476-5365
DOI: 10.1038/bmt.2016.11